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Study Suspects Flame Retardants in Cat Disease

By Home Furnishings Business in Upholstery on August 2007 A mysterious epidemic of thyroid disease among pet cats in the United States may be linked to exposure to dust shed from flame retardants in household carpeting, furniture, fabrics and pet food, scientists reported in a study scheduled for publication in Wednesday’s online issue of Environmental Science & Technology, a semi-monthly journal from the American Chemical Society.

Janice A. Dye, DVM, Ph.D., at the U. S. Environmental Protection Agency in Research Triangle Park, N.C., and colleagues from there and Indiana University and the University of Georgia, reported evidence linking the disease to exposure to environmental contaminants called polybrominated diphenyl ethers (PBDEs), which the researchers found to be elevated in blood samples of hyperthyroid cats. Their findings were based on analysis of blood samples from 23 pet cats, 11 of which had the disease, termed feline hyperthyroidism (FH). PBDE levels in the hyperthyroid cats were three times as high as those in younger, non-hyperthyroid cats.

Concerns about the possible health effects of PDBEs arose in the late 1990s, and studies have reported that PDBEs cause liver and nerve toxicity in animals. FH is one of the most common and deadly diseases in older cats, and indoor pets are thought to be most at-risk. For starters, cats ingest large amounts of PBDE-laden house dust that the researchers believe comes from consumer household products.

With their meticulous grooming behavior, cats may ingest large amounts of dust that collect on their fur.

“Our results showed that cats are being consistently exposed to PBDEs,” Dye said. “Because they are endocrine-disrupting agents, cats may well be at increased risk for developing thyroid effects.”

The epidemic of hyperthyroidism in cats began almost 30 years ago, at the same time when PBDEs were introduced into household materials as a fire-prevention measure. Although the disease was first discovered in the U.S., it has since been diagnosed in Canada, Australia, Japan and many parts of Europe.

“While the link between hyperthyroidism in cats and their elevated PBDE levels requires additional confirmation, it is clear that house cats may be able to serve as sentinels for indoor exposure to PBDEs for humans who share their houses,” said Linda S. Birnbaum, Ph.D., a co-author of the study.

To see the study, click here .

The American Chemical Society is a non-profit organization chartered by the U.S. Congress and a global leader in providing access to chemistry-related research through its multiple databases, peer-reviewed journals and scientific conferences. Its main offices are in Washington D.C., and Columbus, Ohio.


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